The mechanism of hormonal action
1. Indicatethe right answer
Adrenaline activates membrane enzymes
A. Cholinesterase
B. Phosphatase
C. Catalase
D. Glycogensintetase
E. Adenylate cyclase
2. Indicatetheright answer
Adenylate cyclase activates
A. Glucagon
B. Melanotropin
C. Cortisone
D. Progesterone
E. Aldosterone
3. Indicatethe right answer
Adenylate cyclase complex is a
A. Set of cytoplasmic receptors
B. Association of three components: the receptor, and a coupling mechanism catalytic
C. Cytoplasmic multienzyme complex
4. Indicatethe right answer
Cyclic nucleotides
A. Inhibit phosphodiesterase
B. Activates phosphodiesterase
C. Regulate hormone secretion
D. Activate protein kinase capable of phosphorylating proteins
E. Regulate the nerve impulses
F. Inhibit protein kinase
5. Indicatethe right answer
Insulin binds to the target cells
A. Nuclear receptor glycoprotein
B. Glycoprotein cytoplasmic receptors
C. With a mitochondrial glycoprotein receptor
D. Glycoprotein with a receptor on the plasma membrane
6. Indicatethe right answer
Second messenger hormone in the cells are all of the below mentioned except
A. c-GMP
B. Peptides
C. Calcium ions
D. c-AMP
E. Sodium ions
7. Indicatethe right answer
Membrane type of reaction is characteristic of all hormones, except
A. Сatecholamine
B. Tyrosine derivatives
C. Tryptophan derivatives
D. Hormones steroid nature
E. Protein-peptide
8. Indicatethe right answer
Intracellular receptor type characteristic of the hormone is
A. Iodothyronines
B. Сatecholamine
C. Steroid hormones
D. Glucocorticoids
E. Mineralcortikoid
F. Sex
G. Tryptophan derivatives
9. Indicatethe several correct answers
Time stages of hormonal effect in a target cell
A. Early
B. Short
C. Immediate
D. Remote
E. Initial
F. Older
10. Indicate theseveral correct answers
Mediators involved in the implementation ofhormonal effects are all the below mentioned except
A. с-GMP
B. Calcium ions
C. Magnesium ions
D. Of potassium ions
E. Peptides
11. Indicate the right answer
Target cells catecholamines are all the below mentioned except
A. Liver
B. Kidney
C. Adipose tissue
D. Muscle
12. Indicate the right answer
Effects of catecholamines exert via a transmitter
A. Calcium ions
B. Phosphatase
C. Adenylate cyclase
D. Phosphodiesterase
E. Protease
13. Indicate the several correct answers
state hormones, characteristic of membrane cytoreception
A. Estrone
B. Estradiol
C. Insulin
D. Testosterone
E. Adrenaline
F. Cortisone
G. Thyroxine
14. Indicate the several correct answers
Hormones, which act by intracellular reception
A. Adrenaline
B. Glucagon
C. Testosterone
D. Insulin
E. Calcitonin
F. Thyroxine
15. Indicate the several correct answers
Insulin increases membrane permeability to
A. Glucose
B. Potassium ions
C. Sodium
D. Amino acids
E. Phosphate
F. Calcium ions
16. Indicate the several correct answers
membrane permeability of insulin independence are only cells of
A. Erythrocytes
B. Heart
C. Muscle
D. Liver
E. Brain
F. Kidney
17. Indicate the several correct answers
Hormones that bind to receptors located in the cytoplasmic membrane of the cell are
A. Glucagon
B. Androsterone
C. Adrenaline
D. STG
E. Progesterone
18. Indicate the right answer
The hormone binds to the receptor, localized in the cytoplasm of cells is called
A. Insulin
B. Melanoliberin
C. Estradiol
D. Calcitonin
E. Adrenaline
19. Indicate the right answer
The hormone binds to the receptor, localized in the cytoplasm of cells is called
A. Parathyroid hormone
B. Melanostatin
C. Glucagon
D. Insulin
E. Cortisol
20. Indicateseveral correct answers
Insulin deficiency results in the development of
A. Diabetes
B. Steroid diabetes
C. Hypoglycemic coma
D. Hyperlycemic coma
E. Increase in the permeability of cell membranes to glucose
21. Indicateseveral correct answers
hormones, which increase the concentration of glucose in the blood are
A. Mineralocorticoids
B. Glucocorticoids
C. PTH
D. Glucagon
E. Epinephrine
F. Insulin
22. Indicateseveral correct answers
Epinephrine activates
A. Glycogenolysis
B. Lipogenesis
C. Lipolysis
D. Glycolysis
E. Pentose phosphate pathway
23. Indicatethe right answer
Hormone which reduces the concentration of glucose in the blood
A. Glucocorticoids
B. Insulin
C. Epinephrine
D. Glucagon
E. Thyroxine
24. Indicateseveral correct answers
Insulin deficiency leading to hyperglycemia results in
A. The permeability of cell membranes reduction
B. The permeability of cell membranesreduction
C. Acceleration of glycolysis
D. Braking of glycogenesis
E. Inhibition of the Krebs cycle
F. Inhibition of gluconeogenesis
25. Indicatethe right answer
Insulin preparations is not indicated for oral use, because of
A. Inactivated hydrochloric acid
B. Excretion in the feces
C. Binding with bile acids
D. Exposure to proteolysis in the stomach and intestine
E. All the answers are correct
26. Indicateseveral correct answers
Diabetes is happening in case of
A. Reduction in the rate of glycogenolysis
B. Increased activity of acetyl-CoA carboxylase
C. Decreased activity of acetyl-CoA carboxylase
D. An increase in the synthesis of acetoacetate
E. Reduting in the rate of gluconeogenesis
F. Accelerated glycogen synthesis
27. Indicatethe right answer
Insulin which isundercontrolof enzyme glycogen synthesis
A. Glucose 6-phosphatase
B. Glycogen
C. Glycogen phosphorylase
D. Phosphoglucomutase
28. Indicateseveral correct answers
Glycogen is activated by
A. Phosphorylation
B. Dephosphorylation
C. Fructose-1,6-diphosphate
D. Glucose 6-phosphate
E. Glycogen
29. Indicatethe right answer
Hypoglycemia can occur when there is no
A. Hypothyroidism
B. Hyperfunctions of b-cells of islets of Langerhans of the pancreas
C. Hyperparathyroidism
D. Fasting
E. Hypofunction of b-cells of islets of Langerhans of the pancreas
30. Indicateseveral correct answers
Hormonesensitive lipase in adipocyte hormones is activated by
A. Epinephrine
B. Glucagon
C. Thyroxine
D. Cortisone
E. Insulin
31. Indicateseveral correct answers
Hormonesensitivelipase in adipocytesdo not activate such hormones as
A. Thyroxine
B. Epinephrine
C. Cortisone
D. Glucagon
E. Insulin
32. Indicateseveral correct answers
An activator of regulatory enzymes of fatty acids acetyl Coa carboxylase is
A. Malate
B. Insulin
C. Glyconate
D. Citrate
E. Oxaloacetate
33. I ndicatethe right answer
A hormone, which causes a decrease in blood glucose
A. Glucagon
B. Somatotropin
C. Insulin
D. Cortisol
E. Epinephrine
34. Indicatethe right answer
Insulin regulates the process, except
A. Increases the activity of enzymes of glycolysis
B. Increases the permeability of membranes for glucose and amino acids
C. Accelerates the catabolism of proteins
D. Accelerates the utilization of glucose by cells
E. Increases the activity of enzymes pentose phosphate pathway
35. Indicatethe right answer
Glucagon regulates processes
A. Enhances glycogenolysis
B. Accelerates the catabolism of proteins
C. Increases the permeability of cell membranes
D. Enhances the secretion of hormones
E. Accelerates the utilization of glucose by cells
36. Indicatethe right answer
A hormone, which accelerates lipogenesis
A. Epinephrine
B. Thyroxine
C. Insulin
D. Glucagon
E. Calcitonin
37. Indicatethe right answer
Lipolysis further accelerates such hormones as
A. ACTH
B. Glucagon
C. Insulin
D. Somatotropin
E. Epinephrine
38. Indicatethe right answer
A hormone, which accelerates glycolysis
A. Insulin
B. GH
C. Epinephrine
D. ACTH
E. Glucagon
39. Indicatethe several correct answers
A hormones, whichaccelerate the process of glycogenolysis
A. ACTH
B. Epinephrine
C. Glucagon
D. Insulin
E. Thyroxine
F. Glucocorticoids
40. Indicatethe right answer
Hyperglycemic effect is characteristic of allthe hormones, except
A. Glucocorticoids
B. ACTH
C. Epinephrine
D. Insulin
E. Glucagon
41. Indicatethe right answer
Hypoglycemic action is characteristic of the following hormone
A. Parathyroid hormone
B. Insulin
C. Glucocorticoids
D. Glucagon
E. Epinephrine
42. Indicateseveral correct answers
Hypoglycemia leads to the following conditins
A. Weakening of glucagon
B. Decrease of insulin secretion
C. Enhancing of insulin secretion
D. Increased secretion of glucagon
E. The weakening of ACTH secretion
F. The weakening of growth hormone secretion
43. Indicateseveral correct answers
Hyperglycemic conditions leads to
A. Weakeningof insulin secretion
B. Weakening of glucagon
C. Increased secretion of glucagon
D. Increased secretion of ACTH
E. Increased secretion of growth hormone
F. Enhancing of insulin secretion
44. Indicatethe right answer
A hormone, which slows down the process of gluconeogenesis
A. Insulin
B. Epinephrine
C. Glucagon
D. Glucocorticoids
E. ACTH
45. Indicateseveral correct answers
Hormones, whichaccelerate the process of gluconeogenesis
A. Epinephrine
B. Glucocorticoids
C. Glucagon
D. ACTH
E. STG
F. Insulin
46. Indicatethe right answer
Glucagon in adipose tissue activates
A. Acyl-CoA dehydrogenase
B. Pyruvate
C. Lipoprotein lipase
D. Hormonesensitive TAG-lipase
E. Glucose-6-phosphate dehydrogenase
47. Indicateseveral correct answers
CAMP is
A. The membrane receptor for a protein-peptide hormones
B. Phosphodiesterasesubstrate
C. Protein activator
D. The precursor of ATP
A mediator, causing changes in intracellular metabolism
48. Indicatethe right answer
All the statements about hormones are true, except
A. All hormones are synthesized in the anterior pituitary
B. Under the influence of hormones the enzyme activitychanges
C. The effects of hormones are manifested throughinteraction receptor
D. Hormones induce synthesis of enzymes in target cells
E. The synthesis and secretion of hormones is regulated by a feedback mechanism