How to operate your Washamatic

1. Move the Washamatic into a convenient position near your sink. See that all controls are in the OFF position. Remove the lid by sliding it towards the right and gently disengaging from the retaining catch. Attach the adjustable end of the filling hose provided to your tap. This end can be made to fit any size of tap by tightening or loosening the adjuster screw. Fill the tub to the level required, taking care that the water does not rise above the point indicated by the red line running around the inside of the tub. The tub is designed to take a family wash of up to 7 lb. weight of dry clothes. Smaller loads may be washed using less water, but see that the agitator blades are covered to a depth of at least 4". The Washamatic is now ready to be plugged into the electric socket and switched on. switched on.

2. Switch the water heater to ON and move the HEATER control lever upwards until it is opposite the recommended temperature. The temperature automatically controlled and the heater may be left on for the duration of the wash. The heater control lever may be reset if a higher or lower temperature is required. The red indicator light will go out when the water reaches the temperature indicated by the control lever. The heater will bring cold water to the boil if required, but using hot water to fill the tub will enable the correct washing temperature to be reached more quickly.

3. Before washing, see that all tears in the clothes have been mended. Tie loosely any strings, pyjama cords, etc. Sort the washing into groups as recommended in the table below.

Put in the washing, pushing each item into the water separately and distributing evenly around the agitator.

4. Move the WASH control lever to the required time. This will start the washing action. The washer will now be working automatically and may be left until it switches itself off at the right time.

5.Take the clothes from the wash tub and place them in the spin dryer ensuring that they are distributed evenly around the drum. Secure the special retaining lid on top of the drum.

6.Switch the spinner control lever to ON. The spinner will start and suds will be returned to the wash tub.

1.D. CARDIOVASCULAR DRUGS

These drugs may be divided into three groups: drugs that affect the heart; drugs that affect blood pressure; and drugs that prevent blood clotting.

Drugs that affect the heart. Drugs may affect the heart in two major ways: changing the rate and forcefulness of the heartbeat and altering the rhythm of the heartbeat.

Other drugs which belong to the general class of sympathomimetrics are used to increase heart rate and the force of contraction. Drugs used to correct abnormal heart rhythm are called antiarrhythimics.

Drugs that affect blood pressure.Vasodilators are drugs which relax the muscles of vessel walls, thus increasing the size of blood vessels. They are used in treating blood vessel diseases, heart conditions, hypertension. Nitrites are used as vasodilators. Diuretics promote excretion of fluid and shrinkage of the volume of blood within the vessels. Vasoconstrictors are drugs which constrict muscle fibres around blood vessels and narrow the size of the vessel opening.

Drugs that prevent blood clotting. These drugs are called anticoagulants. They are used to prevent the formation of clots in veins and arteries.

ADELPHANE

For the treatment of hypertension

Composition and form of issue

3,4,5 - Trimethoxybenzol-methyl-reserpate

Reserpine is a pure Rauvolfia alkaloid. 1,4 Dihydrazinophthalazine

Dihydralazine is a phthalazine derivative.

Tablets containing 0.1mg reserpine and 10mg dihydralazine sulphate.

Properties

Adelphane contains two components which have different sites of action and whose blood pressure lowering effects are mutually complementary.

Reserpine

Reserpine depletes the catecholamine depots in the post-ganglionic sympathetic nerve endings and in the central nervous system, this depletion being followed by a relatively prolonged inability to store catecholamines. As a result, sympathetic tone diminishes, whereas the activity of the parasympathetic nervous system remains unaffected. Elevated blood pressure is thus lowered, while at the same time the heart rate decreases and a sedative influence is exerted on the central nervous system. As a rule, the maximum response is attained only after 2-3 weeks.

Dihydralazine

By acting directly upon muscle tissue in the blood vessels-primarily in the arterioles-dihydralazine induces peripheral vasodilation, thereby lowering elevated blood pressure. Characteristic of dihydralazine is the fact that is also reduces vascular resistance in the brain and in the kidneys. Renal blood flow is satisfactorily maintained during long-term treatment. Dihydralazine lowers blood pressure in both the standing and the lying position without provoking any marked symptoms of postural hypotension.

Indication

Hypertension

Dosage

The dosage of Adelphane should be individualized. Treatment is initiated with doses as low as possible, which-depending on the patient’s response-may slowly be raised; one should not exceed a daily dosage of 5 tablets. The daily dosage should be taken in 2-3 single doses. For maintenance therapy, the lower dosage that still proves adequate should be employed. On the average, 1-3 tablets daily suffice. The drug should be taken with liquid at mealtimes.

Reserpine

Caution is indicated in patients with a history of gastric or duodenal ulceration, with acute erosive gastritis, or with gallstones, as well as in patients with disorders of cardiac conduction or sinus bradycardia and in those who are known to have suffered from depression in the past.

Dihydralazine

In patients with disorders of hepatic function, a reduction in the dosage or prolongation of the interval between doses may be indicated so as to avoid accumulation.

Unwanted effects

Since the individual components of Adelphane are present in low doses, unwanted effects are likely to be met with only on a small scale, provided the recommended dosage is adhered to Adelphane may nevertheless occasionally give rise to tiredness, muzziness, dizziness, headache, and sleep disturbances. Depression and anxiety states may set in.

Gastro-intestinal upset such as nausea, vomiting, and diarrhoea can occur.

Nasal congestion, flushing, purpura, and sodium and water retention have also been reported.

Higher doses cause postural hypotension.

Storage

Protect from heat, light and humidity.

Packages

Tablets: Boxes of 5 Composite pack of 5x10 in blister packs

Medicines should be kept out of the reach of children.

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